Pasquale Saldarelli devoted his research interests to the study of viral diseases of Mediterranean crops, mainly grapevine, and the investigation of plant virus interactions at molecular level. Results of these studies contributed to the description of new viruses, the development of advanced tools for their detection and the devise of strategies to protect plants from virus infections. Recent research approaches involve the use of next-generation sequencing for virus discovery, metagenome studies, for the dissection of the plant antiviral RNA silencing response in woody plants. He contributed to the description of the draft genome sequence of Xylella fastidiosa CoDiRO. He published 56 ISI-reported publications, collaborated in several EU funded project and coordinate a national R&D project. He is a member of the Committee of the International Council for the Study of Virus and Virus-like Diseases of the Grapevine (ICVG) and of the Italian Society of Phytopathology (SIPaV).